My calorie and macro goals are not updating

Save Settings is required

After changing your values or using the calculator, you still need to click Save Settings to persist the new numbers.

Goal calculator only fills the form

Calculate and apply goals updates the form fields, but it does not save them until you submit Settings.

Unit mismatch

Check whether you are viewing calories in kcal or kJ. A unit mismatch can make the values look wrong even when the save worked.